Skin spots, one of the most hated blemishes, difficult to treat and with multiple causes. To treat them, we often ask ourselves: what to look for in specific treatments? What are the key ingredients? How to navigate the choice of the most suitable cosmetics? All legitimate and correct questions, but the question we must ask ourselves first is: what role does the state of "general skin well-being" play in all this? These questions are answered by her: THE SKIN! Knowing not only the biochemical mechanisms but also the pathophysiological ones that are at the origin of spots, we will find that hypermelanosis should not be attacked but treated, with a view to restoring the state of skin well-being as completely as possible.